Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-
Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-
CAS: 53317-22-9
Molecular Formula: C15H21NO5
Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- - Names and Identifiers
Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- - Physico-chemical Properties
| Molecular Formula | C15H21NO5 |
| Molar Mass | 295.33 |
| Density | 1.174±0.06 g/cm3(Predicted) |
| Boling Point | 456.2±45.0 °C(Predicted) |
| pKa | 3.53±0.10(Predicted) |
Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)- - Introduction
Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-(phenylmethyl)-is a serine-based compound. In its structure, the carboxyl group of serine is linked by oxidation to benzyl and Boc protecting groups.
In terms of properties, this compound is a solid with a white or white-like appearance. It is stable at ambient temperature and soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane.
Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-(phenylmethyl)-has a wide range of uses in the field of organic synthesis. It is often used as a protecting group for serine. The Boc protecting group plays a role in protecting the hydroxyl group in polypeptide synthesis and organic synthesis. Once it is desired to restore the free hydroxyl group of serine, the protecting group can be removed by acid catalysis or hydrogenation reactions.
This compound is generally prepared by reacting serine with a dimethylformamide protecting agent (DMFDMA) in the presence of sodium carbonate to form an intermediate, followed by reaction with benzyl alcohol to obtain the desired product.
Regarding safety information, Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-(phenylmethyl)-has a certain degree of safety under correct operation. However, it may cause irritation to the skin, eyes and respiratory system, so direct contact should be avoided during use. At the same time, appropriate safety measures should be taken in the laboratory environment, such as wearing protective gloves and goggles, and ensuring good ventilation. In case of accidental contact or inhalation, seek medical attention immediately.
In terms of properties, this compound is a solid with a white or white-like appearance. It is stable at ambient temperature and soluble in organic solvents such as dimethylformamide (DMF) and dichloromethane.
Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-(phenylmethyl)-has a wide range of uses in the field of organic synthesis. It is often used as a protecting group for serine. The Boc protecting group plays a role in protecting the hydroxyl group in polypeptide synthesis and organic synthesis. Once it is desired to restore the free hydroxyl group of serine, the protecting group can be removed by acid catalysis or hydrogenation reactions.
This compound is generally prepared by reacting serine with a dimethylformamide protecting agent (DMFDMA) in the presence of sodium carbonate to form an intermediate, followed by reaction with benzyl alcohol to obtain the desired product.
Regarding safety information, Serine, N-[(1,1-dimenthylethoxy) carbonyl]-O-(phenylmethyl)-has a certain degree of safety under correct operation. However, it may cause irritation to the skin, eyes and respiratory system, so direct contact should be avoided during use. At the same time, appropriate safety measures should be taken in the laboratory environment, such as wearing protective gloves and goggles, and ensuring good ventilation. In case of accidental contact or inhalation, seek medical attention immediately.
Last Update：2024-04-10 22:30:50
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